2278278-04-7
2278278-04-7
Chemical Structure
FLT3/ITD-IN-4
- CAS No.: 2278278-04-7
- Formula:C25H22N4O5
- Molecular Weight:458.47
IUPAC Name: 1-(5-(tert-butyl)isoxazol-3-yl)-3-(2-(5-hydroxy-1H-indole-2-carbonyl)benzofuran-5-yl)urea
InChIKey: RADJMCVKNQBZOY-UHFFFAOYSA-N
SMILES: CC(C)(C1=CC(NC(NC2=CC=C3OC(C(C4=CC5=C(N4)C=CC(O)=C5)=O)=CC3=C2)=O)=NO1)C
Biological Activity: FLT3/ITD-IN-4 (Compound 16) is a selective FMS-like tyrosine kinase 3 internal tandem duplications (FLT3-ITD) inhibitor with an IC50 of 2.3 nM. FLT3/ITD-IN-4 can be used for acute myeloid leukemia research[1].
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FLT3/ITD-IN-4 | FLT3/ITD-IN-4 (Compound 16) is a selective FMS-like tyrosine kinase 3 internal tandem duplications (FLT3-ITD) inhibitor with an IC50 of 2.3 nM. FLT3/ITD-IN-4 can be used for acute myeloid leukemia research. | |||||||||||||||||||||
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References
Keywords
