2304750-84-1

CXCR4 antagonist 8 Chemical Structure
2304750-84-1

Chemical Structure

CXCR4 antagonist 8

  • CAS No.: 2304750-84-1
  • Formula:C21H26N6
  • Molecular Weight:362.47

IUPAC Name: N-methyl-N-((2-methyl-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl)methyl)quinolin-8-amine

InChIKey: LBCVTARDQMLTQA-UHFFFAOYSA-N

SMILES: CN1CCN(C2=CC(CN(C)C3=C4N=CC=CC4=CC=C3)=NC(C)=N2)CC1

Biological Activity: CXCR4 antagonist 8 (Compound 3) is a CXCR4 antagonist with an IC50 of 57 nM. CXCR4 antagonist 8 inhibits CXCL12 induced cytosolic calcium increase with an IC50 of 0.24 nM. CXCR4 antagonist 8 inhibits CXLC12/CXCR4 mediated cell migration[1].

Cat. No. Product Name Purity Description Pricing
HY-147978 		CXCR4 antagonist 8 99.88% CXCR4 antagonist 8 (Compound 3) is a CXCR4 antagonist with an IC50 of 57 nM. CXCR4 antagonist 8 inhibits CXCL12 induced cytosolic calcium increase with an IC50 of 0.24 nM. CXCR4 antagonist 8 inhibits CXLC12/CXCR4 mediated cell migration.
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