2341796-73-2
Chemical Structure
(S,R,S)-AHPC-C2-NH2 dihydrochloride
- CAS No.: 2341796-73-2
- Formula:C25H37Cl2N5O4S
- Molecular Weight:574.56
IUPAC Name: (2S,4R)-1-((S)-2-(3-aminopropanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide dihydrochloride
InChIKey: KPAQKVPFCMFPJU-XUKLEHFWSA-N
SMILES: O=C(N(C[C@@H]1O)[C@@H](C1)C(NCC2=CC=C(C(SC=N3)=C3C)C=C2)=O)[C@H](C(C)(C)C)NC(CCN)=O.Cl.Cl
Biological Activity: (S,R,S)-AHPC-C2-NH2 dihydrochloride incorporates a VHL ligand for the E3 ubiquitin ligase, and a PROTAC linker. (S,R,S)-AHPC-OH can be used in the synthesis of a series of PROTACs[1].
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(S,R,S)-AHPC-C2-NH2 dihydrochloride | 98.63% | (S,R,S)-AHPC-C2-NH2 dihydrochloride incorporates a VHL ligand for the E3 ubiquitin ligase, and a PROTAC linker. (S,R,S)-AHPC-OH can be used in the synthesis of a series of PROTACs. | ||||||||||||||||||||
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Keywords