2349393-21-9

KRAS G12C inhibitor 15 Chemical Structure
2349393-21-9

Chemical Structure

KRAS G12C inhibitor 15

  • CAS No.: 2349393-21-9
  • Formula:C25H21ClF2N4O3
  • Molecular Weight:498.91

IUPAC Name: (2R,4aR,10S)-3-acryloyl-11-chloro-9-fluoro-10-(2-fluoro-6-hydroxyphenyl)-2,6-dimethyl-2,3,4,4a-tetrahydro-1H-pyrazino[1',2':4,5]pyrazino[2,3-c]quinolin-5(6H)-one

InChIKey: XDVMVEOFPVCHEL-SJKOYZFVSA-N

SMILES: FC1=C(N=CC(N2C)=C3N4[C@H](CN(C(C=C)=O)[C@H](C)C4)C2=O)C3=CC(Cl)=[C@@]1[C@@]5=C(F)C=CC=C5O

Biological Activity: KRAS G12C inhibitor 15 is a potent KRAS G12C inhibitor extracted from patent WO2019110751A1, compound 22, has an IC50 of 5 nM[1].

Cat. No. Product Name Purity Description Pricing
HY-125873 		KRAS G12C inhibitor 15 98.47% KRAS G12C inhibitor 15 is a potent KRAS G12C inhibitor extracted from patent WO2019110751A1, compound 22, has an IC50 of 5 nM.
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