2383117-96-0
Chemical Structure
IMP-1710
- CAS No.: 2383117-96-0
- Formula:C23H19N5O
- Molecular Weight:381.43
IUPAC Name: (S)-2-(4-(5-ethynyl-1H-pyrrolo[2,3-b]pyridin-3-yl)indoline-1-carbonyl)pyrrolidine-1-carbonitrile
InChIKey: FYMVGXGSNIVSKY-NRFANRHFSA-N
SMILES: O=C([C@H]1N(CCC1)C#N)N2C3=CC=CC(C(C4=C5)=CNC4=NC=C5C#C)=C3CC2
Biological Activity: IMP-1710 is a potent and selective deubiquitylating enzyme UCHL1 inhibitor with an IC50 value of 38 nM. IMP-1710 has antifibrotic activity. IMP-1710 is a UCHL1 probe to identify and quantify target proteins in intact human cells[1]. IMP-1710 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. IMP-1710 can be used in the research of idiopathic pulmonary fibrosis[1].
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IMP-1710 | 98.01% | IMP-1710 is a potent and selective deubiquitylating enzyme UCHL1 inhibitor with an IC50 value of 38 nM. IMP-1710 has antifibrotic activity. IMP-1710 is a UCHL1 probe to identify and quantify target proteins in intact human cells. IMP-1710 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. IMP-1710 can be used in the research of idiopathic pulmonary fibrosis. | ||||||||||||||||||||
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Keywords
