2407465-18-1
Chemical Structure
Farletuzumab ecteribulin
Synonym(s): MORAb-202
- CAS No.: 2407465-18-1
- Formula:N/A
- Molecular Weight:149000 (average)
IUPAC Name: ((2R,3S,4S,5R,6R)-3,4,5-trihydroxy-6-(1H-indol-1-yl)tetrahydro-2H-pyran-2-yl)methyl nicotinate
SMILES: [Farletuzumab ecteribulin]
Biological Activity: Farletuzumab ecteribulin (MORAb-202) is an antibody-drug conjugate (ADC), consisting of the humanized anti-human folate receptor alpha (FRA) antibody Farletuzumab (HY-P99153) conjugated via reduced interchain disulfide bonds to Mal-PEG2-Val-Cit-PAB-eribulin. Farletuzumab ecteribulin has a agent-to-antibody ratio of 4.0. Farletuzumab ecteribulin is highly cytotoxic to FRA-positive cells in vitro. Farletuzumab ecteribulin has potent antitumor activity.
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Farletuzumab ecteribulin | 98.97% | Farletuzumab ecteribulin (MORAb-202) is an antibody-drug conjugate (ADC), consisting of the humanized anti-human folate receptor alpha (FRA) antibody Farletuzumab (HY-P99153) conjugated via reduced interchain disulfide bonds to Mal-PEG2-Val-Cit-PAB-eribulin. Farletuzumab ecteribulin has a agent-to-antibody ratio of 4.0. Farletuzumab ecteribulin is highly cytotoxic to FRA-positive cells in vitro. Farletuzumab ecteribulin has potent antitumor activity. | ||||||||||||||||||||
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Keywords
