2409791-89-3
Chemical Structure
Androgen receptor antagonist 7
- CAS No.: 2409791-89-3
- Formula:C27H35FN2O
- Molecular Weight:422.58
IUPAC Name: (1S,3aS,3bR,5aS,10aS,10bS,12aS)-8-(4-fluorophenyl)-9,10a,12a-trimethyl-1,2,3,3a,3b,4,5,5a,6,8,10,10a,10b,11,12,12a-hexadecahydrocyclopenta[5,6]naphtho[1,2-f]indazol-1-ol
InChIKey: NSUPQZRHRUHVPB-NYKSWYAJSA-N
SMILES: [H][C@@]12CC[C@]3([C@@]4(CC[C@@H]([C@]4(CC[C@@]3([C@]1(CC5=C(N(N=C5C2)C6=CC=C(C=C6)F)C)C)[H])C)O)[H])[H]
Biological Activity: Androgen receptor antagonist 7 is an effective androgen receptor (AR) antagonist with an IC50 value of 1.18 µM. Androgen receptor antagonist 7 has biological activity in vitro and inhibits the expression of AR target in a time and dose dependent manner with an GI50 value of 7.9 µM [1].
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Androgen receptor antagonist 7 | Androgen receptor antagonist 7 is an effective androgen receptor (AR) antagonist with an IC50 value of 1.18 µM. Androgen receptor antagonist 7 has biological activity in vitro and inhibits the expression of AR target in a time and dose dependent manner with an GI50 value of 7.9 µM . | |||||||||||||||||||||
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Keywords
