2413455-99-7
2413455-99-7
Chemical Structure
G-5758
- CAS No.: 2413455-99-7
- Formula:C27H24F4N6O3S
- Molecular Weight:588.58
InChIKey: RBOAUACOQMQNBF-ROUUACIJSA-N
SMILES: FC1=C(F)C(NS(CC2=CC=CC=C2)(=O)=O)=C(F)C=C1OC3=C(C=CC=N3)C4=CC=NC(N[C@H]5C[C@H](F)CNC5)=N4
Biological Activity: G-5758 is a selective and orally effective IRE1α inhibitor with an IC50 of 38 nM (detected by the XBP1s luciferase reporter cell assay). G-5758 is still well tolerated in rats at oral doses up to 500 mg/kg. G-5758 can be used in the research of multiple myeloma[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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G-5758 | 98.91% | G-5758 is a selective and orally effective IRE1α inhibitor with an IC50 of 38 nM (detected by the XBP1s luciferase reporter cell assay). G-5758 is still well tolerated in rats at oral doses up to 500 mg/kg. G-5758 can be used in the research of multiple myeloma. | ||||||||||||||||||||
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References
Keywords
