2413733-73-8
Chemical Structure
MG degrader 3
- CAS No.: 2413733-73-8
- Formula:C24H24ClN3O5
- Molecular Weight:469.92
InChIKey: MRPIWYCYCKIGHP-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(C)C(Cl)=C1)CCCOC2=CC=CC3=C2CN(C(CC4)C(NC4=O)=O)C3=O
Biological Activity: MG degrader 3 is a molecular glue degrader that induces the degradation of multiple proteins including GSPT1, ZFP91 and CK1α via the ubiquitin-proteasome system, regulates protein stability and cellular signaling networks, and exhibits anti-proliferative activity against multiple myeloma cells. MG degrader 3 can be applied in the research of multiple myeloma[1].
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MG degrader 3 | MG degrader 3 is a molecular glue degrader that induces the degradation of multiple proteins including GSPT1, ZFP91 and CK1α via the ubiquitin-proteasome system, regulates protein stability and cellular signaling networks, and exhibits anti-proliferative activity against multiple myeloma cells. MG degrader 3 can be applied in the research of multiple myeloma. | |||||||||||||||||||||
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