2414373-55-8
2414373-55-8
Chemical Structure
CDK6/9-IN-1
- CAS No.: 2414373-55-8
- Formula:C22H25ClN8O
- Molecular Weight:452.94
IUPAC Name: N-(3-((5-chloro-2-((5-(4-methylpiperazin-1-yl)pyridin-2-yl)amino)pyrimidin-4-yl)amino)phenyl)acetamide
InChIKey: GVJLKAACQAJVQS-UHFFFAOYSA-N
SMILES: CC(NC1=CC=CC(NC2=NC(NC3=NC=C(N4CCN(C)CC4)C=C3)=NC=C2Cl)=C1)=O
Biological Activity: CDK6/9-IN-1 (compound 66) is an orally active active and dual CDK 6 and CDK 9 inhibitor, with IC50 values of 40.5 nM and 39.5 nM for CDK6 anmd CDK9, respectively[1].
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CDK6/9-IN-1 | CDK6/9-IN-1 (compound 66) is an orally active active and dual CDK 6 and CDK 9 inhibitor, with IC50 values of 40.5 nM and 39.5 nM for CDK6 anmd CDK9, respectively. | |||||||||||||||||||||
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References
Keywords
