2428742-58-7
2428742-58-7
Chemical Structure
FGFR3-IN-2
- CAS No.: 2428742-58-7
- Formula:C28H39N9O4S
- Molecular Weight:597.73
IUPAC Name: N-ethyl-2-((4-((4-(4-methylpiperazin-1-yl)-3-(2-morpholinoethoxy)phenyl)amino)-1,3,5-triazin-2-yl)amino)benzenesulfonamide
InChIKey: FOZHPNQPNMFWAV-UHFFFAOYSA-N
SMILES: CCNS(=O)(C1=CC=CC=C1NC2=NC(NC3=CC=C(C(OCCN4CCOCC4)=C3)N5CCN(CC5)C)=NC=N2)=O
Biological Activity: FGFR3-IN-2 (compound 18b) is a potent and selective FGFR3 inhibitor, with IC50s of 4.1 nM and 570 nM for FGFR3 and VEGFR2, respectively. FGFR3-IN-2 can be used for the research of bladder cancer[1].
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FGFR3-IN-2 | FGFR3-IN-2 (compound 18b) is a potent and selective FGFR3 inhibitor, with IC50s of 4.1 nM and 570 nM for FGFR3 and VEGFR2, respectively. FGFR3-IN-2 can be used for the research of bladder cancer. | |||||||||||||||||||||
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References
Keywords
