2446474-05-9
2446474-05-9
Chemical Structure
Pomalidomide-C7-NH2 hydrochloride
Synonym(s): Pomalidomide 4'-alkylC7-amine hydrochloride
- CAS No.: 2446474-05-9
- Formula:C20H27ClN4O4
- Molecular Weight:422.91
IUPAC Name: 4-((7-aminoheptyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride
InChIKey: QICRZTGJMYJVAT-UHFFFAOYSA-N
SMILES: O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCCCCCCN)=O.[H]Cl
Biological Activity: Pomalidomide-C7-NH2 (Pomalidomide 4'-alkylC7-amine) hydrochloride is an E3 ligase ligand-linker conjugate. Pomalidomide-C7-NH2 hydrochloride can be used for the synthesis of PROTAC[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Pomalidomide-C7-NH2 hydrochloride | 98.97% | Pomalidomide-C7-NH2 (Pomalidomide 4'-alkylC7-amine) hydrochloride is an E3 ligase ligand-linker conjugate. Pomalidomide-C7-NH2 hydrochloride can be used for the synthesis of PROTAC. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Li Y, et al. Discovery of MD-224 as a First-in-Class, Highly Potent, and Efficacious Proteolysis Targeting Chimera Murine Double Minute 2 Degrader Capable of Achieving Complete and Durable Tumor Regression. J Med Chem. 2019 Jan 24;62(2):448-466. [Content Brief]
- [2]. Si Woo Choi, et al. Hmg-coa reductase degradation inducing compound. Patent, WO2021201577A1.
Keywords
