2450987-57-0
Chemical Structure
Anticancer agent 105
- CAS No.: 2450987-57-0
- Formula:C25H24KN3O6S
- Molecular Weight:533.64
IUPAC Name: potassium (2Z,4Z)-1-amino-2-cyano-4-((3-(ethoxycarbonyl)-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)amino)-6-(4-methoxyphenyl)-1,6-dioxohexa-2,4-dien-3-olate
InChIKey: YNTQHSIVXOWQKC-GGQHYGGTSA-M
SMILES: O=C(OCC)C1=C(NC(/C(O[K])=C(C(N)=O)\C#N)=C\C(C2=CC=C(OC)C=C2)=O)SC3=C1CCCC3
Biological Activity: Anticancer agent 105 is a compound based on thienopyrimidine scaffold, with with good safety and anticancer properties. Anticancer agent 105 shows selective toxicity towards melanoma cancer, and induces apoptosis. And Anticancer agent 105 significantly inhibits the metastatic nodules, even in pulmonary metastatic melanoma mouse model[1].
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Anticancer agent 105 | Anticancer agent 105 is a compound based on thienopyrimidine scaffold, with with good safety and anticancer properties. Anticancer agent 105 shows selective toxicity towards melanoma cancer, and induces apoptosis. And Anticancer agent 105 significantly inhibits the metastatic nodules, even in pulmonary metastatic melanoma mouse model. | |||||||||||||||||||||
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Keywords