2458219-45-7
2458219-45-7
Chemical Structure
SHP2-IN-43
- CAS No.: 2458219-45-7
- Formula:C18H23ClN6OS
- Molecular Weight:406.93
SMILES: ClC(C(SC1=NC=C(N2CCC(N)(CC2)C)N=C1N)=CC=C3)=C3NC(C)=O
Biological Activity: SHP2-IN-43 (Compound 5) is a SHP2 inhibitor with an IC50 of 98.7 nM. SHP2-IN-43 can be used as a PROTAC target ligand in the synthesis of SHP2-D26 (HY-145162)[1].
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SHP2-IN-43 | SHP2-IN-43 (Compound 5) is a SHP2 inhibitor with an IC50 of 98.7 nM. SHP2-IN-43 can be used as a PROTAC target ligand in the synthesis of SHP2-D26 (HY-145162). | |||||||||||||||||||||
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References
Keywords
