SHP2-IN-43
SHP2-IN-43 (Compound 5) is a SHP2 inhibitor with an IC50 of 98.7 nM. SHP2-IN-43 can be used as a PROTAC target ligand in the synthesis of SHP2-D26 (HY-145162).
For research use only. We do not sell to patients.
- CAS No.: 2458219-45-7
- Formula: C18H23ClN6OS
- Molecular Weight:406.93
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MV4-11 | IC50 |
6.6 μM
Compound: 5
|
Growth inhibition of human MV4-11 cells measured after 4 days by WST8 assay
Growth inhibition of human MV4-11 cells measured after 4 days by WST8 assay
|
[PMID: 32437146] |
Chemical Information
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CAS No. 2458219-45-7
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Molecular Weight 406.93
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Formula C18H23ClN6OS
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SMILES
ClC(C(SC1=NC=C(N2CCC(N)(CC2)C)N=C1N)=CC=C3)=C3NC(C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)