2468048-19-1
2468048-19-1
Chemical Structure
BRM/BRG1 ATP-IN-7
- CAS No.: 2468048-19-1
- Formula:C23H21N5O5S2
- Molecular Weight:511.57
InChIKey: OQUVTQILJUJRPX-IBGZPJMESA-N
SMILES: O=C(C1=CN(C=C1)S(C)(=O)=O)N[C@@H](CO)C(NC2=NC(C3=CC(C4=CC=NC=C4)=CC=C3)=CS2)=O
Biological Activity: BRM/BRG1 ATP-IN-7 (Compound Cpd69) is a selective dual BRM (SMARCA2) and BRG1 (SMARCA4) inhibitor with IC50 values of 12 nM and 8 nM, respectively. BRM/BRG1 ATP-IN-7 is promising for research of BRM/BRG1-dependent cancers (e.g., non-small cell lung cancer, Ewing sarcoma) and virus-associated diseases (e.g., HPV infection)[1].
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BRM/BRG1 ATP-IN-7 | BRM/BRG1 ATP-IN-7 (Compound Cpd69) is a selective dual BRM (SMARCA2) and BRG1 (SMARCA4) inhibitor with IC50 values of 12 nM and 8 nM, respectively. BRM/BRG1 ATP-IN-7 is promising for research of BRM/BRG1-dependent cancers (e.g., non-small cell lung cancer, Ewing sarcoma) and virus-associated diseases (e.g., HPV infection). | |||||||||||||||||||||
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References
Keywords
