2477651-11-7
Chemical Structure
USP8-IN-2
- CAS No.: 2477651-11-7
- Formula:C19H20ClF3N4OS
- Molecular Weight:444.90
IUPAC Name: 1-(5-chloro-2-methoxyphenyl)-3-(1-(6-(trifluoromethyl)pyridin-2-yl)piperidin-4-yl)thiourea
InChIKey: XKLBIJSKEVHKCM-UHFFFAOYSA-N
SMILES: FC(F)(C1=NC(N2CCC(CC2)NC(NC3=CC(Cl)=CC=C3OC)=S)=CC=C1)F
Biological Activity: USP8-IN-2 (Compd U52) is a deubiquitinase USP8 inhibitor with an IC50 value of 6.0 μM. USP8-IN-2 also inhibits the proliferation of H1957 cells with an GI50 value of 24.93 μM, respectively[1].
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USP8-IN-2 | 99.91% | USP8-IN-2 (Compd U52) is a deubiquitinase USP8 inhibitor with an IC50 value of 6.0 μM. USP8-IN-2 also inhibits the proliferation of H1957 cells with an GI50 value of 24.93 μM, respectively. | ||||||||||||||||||||
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Keywords