2485135-31-5

Topoisomerase I inhibitor 4 Chemical Structure
2485135-31-5

Chemical Structure

Topoisomerase I inhibitor 4

  • CAS No.: 2485135-31-5
  • Formula:C23H19FN4O
  • Molecular Weight:386.42

IUPAC Name: 2-fluoro-3-(piperazin-1-yl)benzo[5,6]isoindolo[1,2-b]quinazolin-14(12H)-one

InChIKey: LCHXXXKCDTVPMB-UHFFFAOYSA-N

SMILES: O=C1C2=C(N=C3C4=CC5=CC=CC=C5C=C4CN13)C=C(C(F)=C2)N6CCNCC6

Biological Activity: Topoisomerase I inhibitor 4 (compound 7a) is a topoisomerase I inhibitor. Topoisomerase I inhibitor 4 inhibits HepG2, A549, MCF-7 and HeLa cancer cells proliferation with IC50s of 1.20, 2.09, 1.56 and 1.92 μM, respectively. Topoisomerase I inhibitor 4 can be used for the research of cancer[1].

Cat. No. Product Name Purity Description Pricing
HY-143301 		Topoisomerase I inhibitor 4 Topoisomerase I inhibitor 4 (compound 7a) is a topoisomerase I inhibitor. Topoisomerase I inhibitor 4 inhibits HepG2, A549, MCF-7 and HeLa cancer cells proliferation with IC50s of 1.20, 2.09, 1.56 and 1.92 μM, respectively. Topoisomerase I inhibitor 4 can be used for the research of cancer.
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