2488788-52-7

RMC-0331 Chemical Structure
2488788-52-7

Chemical Structure

RMC-0331

Synonym(s): RM-023

  • CAS No.: 2488788-52-7
  • Formula:C22H25ClF3N5O3
  • Molecular Weight:499.91

IUPAC Name: (R)-(4-((1-(3-amino-5-(trifluoromethyl)phenyl)ethyl)amino)-2-chloro-5,7-dihydro-6H-pyrrolo[3,4-d]pyrimidin-6-yl)(4-methoxytetrahydro-2H-pyran-4-yl)methanone

InChIKey: HOBOGRTXXDLZIB-GFCCVEGCSA-N

SMILES: O=C(N1CC2=NC(Cl)=NC(N[C@@H](C3=CC(C(F)(F)F)=CC(N)=C3)C)=C2C1)C4(OC)CCOCC4

Biological Activity: RMC-0331 (RM-023) is a potent, selective and orally bioavailable SOS1 inhibitor. RMC-0331 is an in vivo tool compound that blocks RAS activation via disruption of the RAS-SOS1 interaction[1].

Cat. No. Product Name Purity Description Pricing
HY-134885
RMC-0331 98.96% RMC-0331 (RM-023) is a potent, selective and orally bioavailable SOS1 inhibitor. RMC-0331 is an in vivo tool compound that blocks RAS activation via disruption of the RAS-SOS1 interaction.
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