2490402-62-3
2490402-62-3
Chemical Structure
Thalidomide-5-propargyne-NH2 hydrochloride
- CAS No.: 2490402-62-3
- Formula:C16H14ClN3O4
- Molecular Weight:347.75
IUPAC Name: 5-(3-aminoprop-1-yn-1-yl)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride
InChIKey: XOXKGOUHXULLNX-UHFFFAOYSA-N
SMILES: O=C1C2=CC=C(C=C2C(N1C3C(NC(CC3)=O)=O)=O)C#CCN.Cl
Biological Activity: Thalidomide-5-propargyne-NH2 hydrochloride is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5-propargyne-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Thalidomide-5-propargyne-NH2 hydrochloride | 98.03% | Thalidomide-5-propargyne-NH2 hydrochloride is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5-propargyne-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs. | ||||||||||||||||||||
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References
