2499965-12-5
2499965-12-5
Chemical Structure
PD-1/PD-L1-IN-14
- CAS No.: 2499965-12-5
- Formula:C24H24N4O2
- Molecular Weight:400.47
IUPAC Name: 2-((3-((5-(2-methyl-[1,1'-biphenyl]-3-yl)-1,3,4-oxadiazol-2-yl)amino)benzyl)amino)ethan-1-ol
InChIKey: YBHXMLDVPTWSAS-UHFFFAOYSA-N
SMILES: CC1=C(C2=NN=C(NC3=CC(CNCCO)=CC=C3)O2)C=CC=C1C4=CC=CC=C4
Biological Activity: PD-1/PD-L1-IN-14 (compound 17) is a bifunctional inhibitor of PD-1/PD-L1 interactions, with an IC50 of 27.8 nM. PD-1/PD-L1-IN-14 (compound 17) inhibits PD-1/PD-L1 interactions and promotes dimerization, internalization, and degradation of PD-L1[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PD-1/PD-L1-IN-14 | 99.60% | PD-1/PD-L1-IN-14 (compound 17) is a bifunctional inhibitor of PD-1/PD-L1 interactions, with an IC50 of 27.8 nM. PD-1/PD-L1-IN-14 (compound 17) inhibits PD-1/PD-L1 interactions and promotes dimerization, internalization, and degradation of PD-L1. | ||||||||||||||||||||
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References
Keywords
