2517584-04-0
Chemical Structure
Isoprenaline-d7 hydrochloride
Synonym(s): Isoproterenol-d7 hydrochloride
- CAS No.: 2517584-04-0
- Formula:C11H11D7ClNO3
- Molecular Weight:254.76
IUPAC Name: 4-(1-hydroxy-2-((propan-2-yl-d7)amino)ethyl)benzene-1,2-diol hydrochloride
InChIKey: IROWCYIEJAOFOW-AUYCXRIESA-N
SMILES: [2H]C([2H])([2H])C(C([2H])([2H])[2H])([2H])NCC(C1=CC(O)=C(C=C1)O)O.Cl
Biological Activity: Isoprenaline-d7 (hydrochloride) is a deuterated labeled Isoprenaline (hydrochloride)[1]. Isoprenaline (Isoproterenol) hydrochloride is a non-selective, orally active β-adrenergic receptor agonist. Isoprenaline has potent peripheral vasodilator, bronchodilator, and cardiac stimulating activities. Isoprenaline can be used for the research of bradycardia and bronchial asthma[2][3][4][5][6][7].
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Isoprenaline-d7 hydrochloride | Isoprenaline-d7 (hydrochloride) is a deuterated labeled Isoprenaline (hydrochloride). Isoprenaline (Isoproterenol) hydrochloride is a non-selective, orally active β-adrenergic receptor agonist. Isoprenaline has potent peripheral vasodilator, bronchodilator, and cardiac stimulating activities. Isoprenaline can be used for the research of bradycardia and bronchial asthma. | |||||||||||||||||||||
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Isoprenaline hydrochloride (Standard) | ≥98% | Isoprenaline (hydrochloride) (Standard) is the analytical standard of Isoprenaline (hydrochloride). This product is intended for research and analytical applications. Isoprenaline (Isoproterenol) hydrochloride is a non-selective, orally active β-adrenergic receptor agonist. Isoprenaline has potent peripheral vasodilator, bronchodilator, and cardiac stimulating activities. Isoprenaline can be used for the research of bradycardia and bronchial asthma. | ||||||||||||||||||||
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Isoprenaline hydrochloride | 99.86% | Isoprenaline (Isoproterenol) hydrochloride is a non-selective, orally active β-adrenergic receptor agonist. Isoprenaline has potent peripheral vasodilator, bronchodilator, and cardiac stimulating activities. Isoprenaline can be used for the research of bradycardia and bronchial asthma. | ||||||||||||||||||||
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- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
- [2]. Degerman E, et al. Evidence that insulin and isoprenaline activate the cGMP-inhibited low-Km cAMP phosphodiesterase in rat fat cells by phosphorylation. Proc Natl Acad Sci U S A. 1990 Jan;87(2):533-7 [Content Brief]
- [3]. Vannucci SJ, et al. Cell surface accessibility of GLUT4 glucose transporters in insulin-stimulated rat adipose cells. Modulation by isoprenaline and adenosine. Biochem J. 1992 Nov 15;288 (Pt 1):325-30. [Content Brief]
- [4]. M E Conolly, et al. Metabolism of isoprenaline in dog and man. Br J Pharmacol [Content Brief]
- [5]. Lei M, et al. Modulation of delayed rectifier potassium current, iK, by isoprenaline in rabbit isolated pacemaker cells. Exp Physiol. 2000 Jan;85(1):27-35. [Content Brief]
- [6]. Delpy E, et al. Effects of cyclic GMP elevation on isoprenaline-induced increase in cyclic AMP and relaxation in rat aortic smooth muscle: role of phosphodiesterase 3. Br J Pharmacol. 1996 Oct;119(3):471-8. [Content Brief]
- [7]. Muller FU, et al. Isoprenaline stimulates gene transcription of the inhibitory G protein alpha-subunit Gi alpha-2 in rat heart. Circ Res. 1993 Mar;72(3):696-700. [Content Brief]
