2547100-02-5
Chemical Structure
N2S2-CBMBC
- CAS No.: 2547100-02-5
- Formula:C34H33BrClN3O3S2
- Molecular Weight:711.13
IUPAC Name: 2-((4-((2-bromo-[1,1'-biphenyl]-3-yl)methoxy)-5-chloro-2-((3-cyanobenzyl)oxy)benzyl)(2-mercaptoethyl)amino)-N-(2-mercaptoethyl)acetamide
InChIKey: IYHXDWWOGKOFEN-UHFFFAOYSA-N
SMILES: N#CC1=CC=CC(COC2=CC(OCC3=CC=CC(C4=CC=CC=C4)=C3Br)=C(C=C2CN(CCS)CC(NCCS)=O)Cl)=C1
Biological Activity: N2S2-CBMBC, an N2S2 bromo-benzyl ether derivative, acts as a ligand and use 99mTc-labelled complexes 99mTc-N2S2-CBMBC can be used as an imaging agent to be applied to the aspect of detecting PD-L1 expression, realize the real-time, comprehensive and convenient detection of the PD-L1 level of tumors, and overcome the defects of an immunohistochemical method[1].
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N2S2-CBMBC | N2S2-CBMBC, an N2S2 bromo-benzyl ether derivative, acts as a ligand and use 99mTc-labelled complexes 99mTc-N2S2-CBMBC can be used as an imaging agent to be applied to the aspect of detecting PD-L1 expression, realize the real-time, comprehensive and convenient detection of the PD-L1 level of tumors, and overcome the defects of an immunohistochemical method. | |||||||||||||||||||||
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Keywords
