2551067-10-6
Chemical Structure
Apoptosis inducer 9
- CAS No.: 2551067-10-6
- Formula:C34H55N3O4S
- Molecular Weight:601.88
IUPAC Name: (3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-4,4,8,10,14-pentamethyl-17-((R)-2,6,6-trimethyltetrahydro-2H-pyran-2-yl)hexadecahydro-1H-cyclopenta[a]phenanthren-3-yl 2-((4H-1,2,4-triazol-3-yl)thio)acetate
InChIKey: BQKBVOVTODBTCP-PZFAUQBASA-N
SMILES: C[C@]12[C@@](C[C@H]([C@@]3([H])[C@]2(CC[C@]3([H])[C@@]4(OC(C)(CCC4)C)C)C)O)([H])[C@@]5([C@@](C(C)([C@H](CC5)OC(CSC6=NN=CN6)=O)C)([H])CC1)C
Biological Activity: Apoptosis inducer 9 induces apoptosis with IC50 value of 4.21 μM. Apoptosis inducer 9 induces apoptosis through the mitochondrial pathway and enhance the expression of Cl-caspase-3, Cl-caspase-9 and Cl-PARP. Apoptosis inducer 9 can be used the potential to develop new anti-proliferative agents[1].
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Apoptosis inducer 9 | Apoptosis inducer 9 induces apoptosis with IC50 value of 4.21 μM. Apoptosis inducer 9 induces apoptosis through the mitochondrial pathway and enhance the expression of Cl-caspase-3, Cl-caspase-9 and Cl-PARP. Apoptosis inducer 9 can be used the potential to develop new anti-proliferative agents. | |||||||||||||||||||||
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Keywords
