2573302-50-6
2573302-50-6
Chemical Structure
KTX-955
- CAS No.: 2573302-50-6
- Formula:C46H51F3N8O7
- Molecular Weight:884.94
IUPAC Name: (S)-2-amino-3-cyano-4-methyl-4,5,6,7-tetrahydrobenzo[b]thiophene-4-carboxylic acid
InChIKey: KLKZEZBWHOQDRM-FDNLEIHHSA-N
SMILES: O=C(N1C2C(NC(CC2)=O)=O)C3=CC=CC(N[C@H]4C[C@@H](C4)OC5CCN(CC5)C[C@H]6CC[C@H](N7C=C8C(C=C(C(NC(C9=CC=CC(C(F)(F)F)=N9)=O)=C8)C(C)(O)C)=N7)CC6)=C3C1=O
Biological Activity: KTX-955 is an antumor and effective IRAK4 degrader, with DC50 values of 5 nM and 130 nM for IRAK4 and Ikaros, respectively[1].
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KTX-955 | KTX-955 is an antumor and effective IRAK4 degrader, with DC50 values of 5 nM and 130 nM for IRAK4 and Ikaros, respectively. | |||||||||||||||||||||
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References
Keywords
