2581082-74-6
2581082-74-6
Chemical Structure
Antitumor agent-45
- CAS No.: 2581082-74-6
- Formula:C28H17BrFN5O3
- Molecular Weight:570.37
IUPAC Name: N-(4-((1H-pyrrolo[2,3-b]pyridin-4-yl)oxy)-3-fluorophenyl)-1-(4-bromophenyl)-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxamide
InChIKey: OKCVLHCOWSNRPV-UHFFFAOYSA-N
SMILES: O=C(C1=CN(C2=NC=CC=C2C1=O)C3=CC=C(C=C3)Br)NC4=CC=C(C(F)=C4)OC5=CC=NC6=C5C=CN6
Biological Activity: Antitumor agent-45 (Compound 21) could induce and stimulate A549 cells apoptosis in G0/G1 and G2/M phase. Antitumor agent-45 (Compound 21) inhibits c-Met expression to regulate the growth of tumor cells[1].
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Antitumor agent-45 | Antitumor agent-45 (Compound 21) could induce and stimulate A549 cells apoptosis in G0/G1 and G2/M phase. Antitumor agent-45 (Compound 21) inhibits c-Met expression to regulate the growth of tumor cells. | |||||||||||||||||||||
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References
Keywords
