2581824-80-6
2581824-80-6
Chemical Structure
MMP-9-IN-5
- CAS No.: 2581824-80-6
- Formula:C27H20IN3O4
- Molecular Weight:577.37
IUPAC Name: 2-iodo-N-(2-((4-nitrophenyl)amino)-2-oxo-1-phenylethyl)-N-phenylbenzamide
InChIKey: MIENZPZOHXCZQM-UHFFFAOYSA-N
SMILES: O=C(C(N(C1=CC=CC=C1)C(C2=C(I)C=CC=C2)=O)C3=CC=CC=C3)NC4=CC=C(C=C4)[N+]([O-])=O
Biological Activity: MMP-9-IN-5 is a MMP-9 inhibitor (IC50: 4.49 nM) that forms hydrogen bond with MMP-9. MMP-9-IN-5 also inhibits AKT activity (IC50: 1.34 nM). MMP-9-IN-5 shows cell cytotoxicity and induces cell apoptosis. MMP-9-IN-5 can be used in the research of cancers[1].
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MMP-9-IN-5 | MMP-9-IN-5 is a MMP-9 inhibitor (IC50: 4.49 nM) that forms hydrogen bond with MMP-9. MMP-9-IN-5 also inhibits AKT activity (IC50: 1.34 nM). MMP-9-IN-5 shows cell cytotoxicity and induces cell apoptosis. MMP-9-IN-5 can be used in the research of cancers. | |||||||||||||||||||||
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References
Keywords
