2597353-33-6
2597353-33-6
Chemical Structure
N1,N8-Diacetylspermidine-d6
- CAS. Nr.: 2597353-33-6
- Formula:C11H17D6N3O2
- Molecular Weight:235.36
InChIKey: BKCVMAZDKFQPHB-WFGJKAKNSA-N
SMILES: O=C(C([2H])([2H])[2H])NCCCCNCCCNC(C([2H])([2H])[2H])=O
Biological Activity: N1,N8-Diacetylspermidine-d6 is the deuterium labeled N1,N8-Diacetylspermidine (HY-129912). N1,N8-Diacetylspermidine is a polyamines in the human urine[1]. N1,N8-Diacetylspermidine is useful as prognostic indicators after treatment and during follow-up examination of cancer patients[2].
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N1,N8-Diacetylspermidine-d6 | N1,N8-Diacetylspermidine-d6 is the deuterium labeled N1,N8-Diacetylspermidine (HY-129912). N1,N8-Diacetylspermidine is a polyamines in the human urine. N1,N8-Diacetylspermidine is useful as prognostic indicators after treatment and during follow-up examination of cancer patients. | |||||||||||||||||||||
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N1,N8-Diacetylspermidine | 99.96% | N1,N8-Diacetylspermidine is a diacetylated polyamine metabolite and also a urine biomarker associated with diagnosis, prognosis and disease severity. Urinary levels of N1,N8-Diacetylspermidine increase in breast cancer, colorectal cancer, urogenital malignancies and Parkinson's disease. N1,N8-Diacetylspermidine can be used in studies related to breast cancer, colorectal cancer, urogenital malignancies and Parkinson's disease. | ||||||||||||||||||||
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References
- [1]. Umemori Y, et al. Evaluating the utility of N1,N12-diacetylspermine and N1,N8-diacetylspermidine in urine as tumormarkers for breast and colorectal cancers. Clin Chim Acta. 2010 Dec 14;411(23-24):1894-9. [Content Brief]
- [2]. Hiramatsu K, et al. Diagnostic and prognostic usefulness of N1,N8-diacetylspermidine and N1,N12-diacetylsperminein urine as novel markers of malignancy. J Cancer Res Clin Oncol. 1997;123(10):539-45 [Content Brief]
