2611373-80-7
2611373-80-7
Chemical Structure
Tenofovir-C3-O-C15-CF3 ammonium
- CAS No.: 2611373-80-7
- Formula:C28H52F3N6O5P
- Molecular Weight:640.72
IUPAC Name: ammonium 3-((16,16,16-trifluorohexadecyl)oxy)propyl (R)-(((1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate
InChIKey: MAVYHINXUMVIRW-GJFSDDNBSA-N
SMILES: FC(F)(F)CCCCCCCCCCCCCCCOCCCOP(CO[C@H](C)CN1C=NC2=C1N=CN=C2N)([O-])=O.[NH4+]
Biological Activity: Tenofovir-C3-O-C15-CF3 (ammonium) exhibits substantially longer t1/2 values than tenofovir in human liver microsomes, potent anti-HIV activity in vitro, and enhances pharmacokinetic properties in vivo.
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Tenofovir-C3-O-C15-CF3 ammonium | Tenofovir-C3-O-C15-CF3 (ammonium) exhibits substantially longer t1/2 values than tenofovir in human liver microsomes, potent anti-HIV activity in vitro, and enhances pharmacokinetic properties in vivo. | |||||||||||||||||||||
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Keywords
