Tenofovir-C3-O-C15-CF3 ammonium
Tenofovir-C3-O-C15-CF3 (ammonium) exhibits substantially longer t1/2 values than tenofovir in human liver microsomes, potent anti-HIV activity in vitro, and enhances pharmacokinetic properties in vivo.
For research use only. We do not sell to patients.
- CAS No.: 2611373-80-7
- Formula: C28H52F3N6O5P
- Molecular Weight:640.72
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK-293T | CC50 |
>100 μM
Compound: 21
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Cytotoxicity against HEK293T cells assessed as reduction in cell viability measured after 48 hrs by CellTiter 96 Aqueous One Solution reagent based cell proliferation assay
Cytotoxicity against HEK293T cells assessed as reduction in cell viability measured after 48 hrs by CellTiter 96 Aqueous One Solution reagent based cell proliferation assay
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[PMID: 34459598] |
Chemical Information
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CAS No. 2611373-80-7
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Molecular Weight 640.72
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Formula C28H52F3N6O5P
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SMILES
FC(F)(F)CCCCCCCCCCCCCCCOCCCOP(CO[C@H](C)CN1C=NC2=C1N=CN=C2N)([O-])=O.[NH4+]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Tenofovir-C3-O-C15-CF3 ammonium Related Classifications
HY-139721 Related Classifications
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