2637949-91-6

XL44 Chemical Structure
2637949-91-6

Chemical Structure

XL44

  • CAS No.: 2637949-91-6
  • Formula:C23H17FN2O3
  • Molecular Weight:388.39

InChIKey: UOTAUCCFVUPGRQ-NDENLUEZSA-N

SMILES: O=C(C1=CC=C(OC)C=C1)NC2=CC=CC(/C=C3C(NC4=C\3C=C(F)C=C4)=O)=C2

Biological Activity: XL44, an hRpn13 binder, induces hRpn13-dependent apoptosis and also restricts cell viability by a PCLAF-dependent mechanism. XL44 induces ubiquitin-dependent loss of hRpn13Pru and ubiquitin-independent loss of select KEN box containing proteins[1].

Cat. No. Product Name Purity Description Pricing
HY-162393
XL44 99.76% XL44, an hRpn13 binder, induces hRpn13-dependent apoptosis and also restricts cell viability by a PCLAF-dependent mechanism. XL44 induces ubiquitin-dependent loss of hRpn13Pru and ubiquitin-independent loss of select KEN box containing proteins.
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