2639542-22-4
2639542-22-4
Chemical Structure
CDK5-IN-2
- CAS No.: 2639542-22-4
- Formula:C29H28FN5O
- Molecular Weight:481.56
IUPAC Name: (R)-3'-fluoro-4'-((2-(1-hydroxy-1-(1-methylpiperidin-4-yl)ethyl)-1,6-naphthyridin-7-yl)amino)-[1,1'-biphenyl]-3-carbonitrile
InChIKey: KKNXJZMTIWJEEF-GDLZYMKVSA-N
SMILES: FC1=CC(C2=CC=CC(C#N)=C2)=CC=C1NC3=CC4=NC([C@](C)(O)C5CCN(C)CC5)=CC=C4C=N3
Biological Activity: CDK5-IN-2 (compound 15) is a highly selective CDK5 inhibitor with IC50s of 0.2 and 23 for CDK5/p25 and CDK2/CycA, respectively[1].
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CDK5-IN-2 | CDK5-IN-2 (compound 15) is a highly selective CDK5 inhibitor with IC50s of 0.2 and 23 for CDK5/p25 and CDK2/CycA, respectively. | |||||||||||||||||||||
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References
Keywords
