2641510-88-3
2641510-88-3
Chemical Structure
PROTAC SMARCA2 degrader-28
- CAS No.: 2641510-88-3
- Formula:C50H51F7N10O10
- Molecular Weight:1084.99
InChIKey: KJFXSDIHISMYCX-UHFFFAOYSA-N
SMILES: OC1=C(C2=CC(N3CC4N(C5=CC=CC(CN6CCN(C(C7CCN(C8=CC(C(N(C9CCC(NC9=O)=O)C%10=O)=O)=C%10C=C8)CC7)=O)CC6)=C5)C(CC4)C3)=C(N)N=N2)C=C(F)C=C1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F
Biological Activity: PROTAC SMARCA2 degrader-28 (Compound 158) is a PROTAC degrader for SMARCA2, that degrades SMARCA2 with a DC50 of 3 nM in HiBiT A549 cells[1].
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PROTAC SMARCA2 degrader-28 | PROTAC SMARCA2 degrader-28 (Compound 158) is a PROTAC degrader for SMARCA2, that degrades SMARCA2 with a DC50 of 3 nM in HiBiT A549 cells. | |||||||||||||||||||||
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References
Keywords
