PROTAC SMARCA2 degrader-28
PROTAC SMARCA2 degrader-28 (Compound 158) is a PROTAC degrader for SMARCA2, that degrades SMARCA2 with a DC50 of 3 nM in HiBiT A549 cells.
(Pink: SMARCA2 ligand (HY-168237); Blue: Cereblon ligand (HY-W087383); Black: linker (HY-168238)).
For research use only. We do not sell to patients.
- CAS No.: 2641510-88-3
- Formula: C50H51F7N10O10
- Molecular Weight:1084.99
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 2641510-88-3
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Molecular Weight 1084.99
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Formula C50H51F7N10O10
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SMILES
OC1=C(C2=CC(N3CC4N(C5=CC=CC(CN6CCN(C(C7CCN(C8=CC(C(N(C9CCC(NC9=O)=O)C%10=O)=O)=C%10C=C8)CC7)=O)CC6)=C5)C(CC4)C3)=C(N)N=N2)C=C(F)C=C1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)