2648206-31-7
Chemical Structure
EGFR-IN-21
- CAS No.: 2648206-31-7
- Formula:C36H44BrN10O2P
- Molecular Weight:759.68
IUPAC Name: (3-((5-bromo-2-((2-methoxy-5-(1-methyl-1H-pyrazol-4-yl)-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)amino)pyrimidin-4-yl)amino)quinolin-4-yl)dimethylphosphine oxide
InChIKey: LSEIPGIXLLFPNX-UHFFFAOYSA-N
SMILES: O=P(C)(C)C1=C2C=CC=CC2=NC=C1NC3=NC(NC4=CC(C5=CN(C)N=C5)=C(N6CCC(CC6)N7CCN(CC7)C)C=C4OC)=NC=C3Br
Biological Activity: EGFR-IN-21 is a potent EGFR inhibtior with an IC50 of 0.38 nM. EGFR-IN-21 has antitumor activity[1].
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EGFR-IN-21 | EGFR-IN-21 is a potent EGFR inhibtior with an IC50 of 0.38 nM. EGFR-IN-21 has antitumor activity. | |||||||||||||||||||||
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Keywords