2649170-17-0

TLR7/8 agonist 9 Chemical Structure
2649170-17-0

Chemical Structure

TLR7/8 agonist 9

  • CAS No.: 2649170-17-0
  • Formula:C20H26N6O
  • Molecular Weight:366.46

IUPAC Name: 6-(4-((dimethylamino)methyl)benzyl)-N4-(2-methoxyethyl)pyrido[3,2-d]pyrimidine-2,4-diamine

InChIKey: UQHYCVOVYJQJOY-UHFFFAOYSA-N

SMILES: NC1=NC(NCCOC)=C2C(C=CC(CC3=CC=C(CN(C)C)C=C3)=N2)=N1

Biological Activity: TLR7/8 agonist 9 (Compound 25a) is a TLR7/8 agonist, with EC50s of 40 nM and 23 nM for hTLR7/8. TLR7/8 agonist 9 has anti-tumor activity and improves the antitumor activity of PD-1/PD-L1 blockade. TLR7/8 agonist 9 can be used for research of cancer immunotherapy[1].

Cat. No. Product Name Purity Description Pricing
HY-153544 		TLR7/8 agonist 9 TLR7/8 agonist 9 (Compound 25a) is a TLR7/8 agonist, with EC50s of 40 nM and 23 nM for hTLR7/8. TLR7/8 agonist 9 has anti-tumor activity and improves the antitumor activity of PD-1/PD-L1 blockade. TLR7/8 agonist 9 can be used for research of cancer immunotherapy.
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