TLR7/8 agonist 9
TLR7/8 agonist 9 (Compound 25a) is a TLR7/8 agonist, with EC50s of 40 nM and 23 nM for hTLR7/8. TLR7/8 agonist 9 has anti-tumor activity and improves the antitumor activity of PD-1/PD-L1 blockade. TLR7/8 agonist 9 can be used for research of cancer immunotherapy.
For research use only. We do not sell to patients.
- CAS No.: 2649170-17-0
- Formula: C20H26N6O
- Molecular Weight:366.46
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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TLR7 |
TLR8 |
Chemical Information
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CAS No. 2649170-17-0
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Molecular Weight 366.46
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Formula C20H26N6O
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SMILES
NC1=NC(NCCOC)=C2C(C=CC(CC3=CC=C(CN(C)C)C=C3)=N2)=N1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TLR7/8 agonist 9 Related Classifications
HY-153544 Related Classifications
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