2653254-31-8
Chemical Structure
TYA-018
- CAS No.: 2653254-31-8
- Formula:C15H13ClF2N4O3S2
- Molecular Weight:434.87
IUPAC Name: N-(3-chlorophenyl)-N-((5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)thiazol-2-yl)methyl)ethanesulfonamide
InChIKey: DAMJZODYLBMFHQ-UHFFFAOYSA-N
SMILES: O=S(N(CC1=NC=C(C2=NN=C(C(F)F)O2)S1)C3=CC(Cl)=CC=C3)(CC)=O
Biological Activity: TYA-018 is an orally active, potent and highly selective HDAC6 inhibitor. TYA-018 can protect heart function in mice. TYA-018 also enhances energetics in mice by increasing expression of targets associated with fatty acid metabolism, protein metabolism, and oxidative phosphorylation[1].
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TYA-018 | 99.84% | TYA-018 is an orally active, potent and highly selective HDAC6 inhibitor. TYA-018 can protect heart function in mice. TYA-018 also enhances energetics in mice by increasing expression of targets associated with fatty acid metabolism, protein metabolism, and oxidative phosphorylation. | ||||||||||||||||||||
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Keywords
