2653338-54-4
2653338-54-4
Chemical Structure
Thalidomide-4-O-C7-Br
- CAS No.: 2653338-54-4
- Formula:C20H23BrN2O5
- Molecular Weight:451.31
InChIKey: AHHJPVPXTRCELK-UHFFFAOYSA-N
SMILES: BrCCCCCCCOC1=C2C(C(N(C2=O)C3C(NC(CC3)=O)=O)=O)=CC=C1
Biological Activity: Thalidomide-4-O-C7-Br is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based CRBN ligand and a linker used in PROTAC technology. Thalidomide-4-O-C7-Br can be connected to the ligand for protein by a linker to form PROTAC FAK degrader 3 (HY-175459)[1].
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Thalidomide-4-O-C7-Br | Thalidomide-4-O-C7-Br is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based CRBN ligand and a linker used in PROTAC technology. Thalidomide-4-O-C7-Br can be connected to the ligand for protein by a linker to form PROTAC FAK degrader 3 (HY-175459). | |||||||||||||||||||||
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References
Keywords
