Thalidomide-4-O-C7-Br
Thalidomide-4-O-C7-Br is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based CRBN ligand and a linker used in PROTAC technology. Thalidomide-4-O-C7-Br can be connected to the ligand for protein by a linker to form PROTAC FAK degrader 3 (HY-175459).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2653338-54-4
- 分子式: C20H23BrN2O5
- 分子量:451.31
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
E3 Ligase Ligand-Linker Conjugates アイソフォーム固有の製品をすべて表示
More
生物活性
製品説明
体外実験
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 2653338-54-4
-
分子量 451.31
-
分子式 C20H23BrN2O5
-
SMILES
BrCCCCCCCOC1=C2C(C(N(C2=O)C3C(NC(CC3)=O)=O)=O)=CC=C1
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)