2672508-37-9
Chemical Structure
LXJ-02
- CAS No.: 2672508-37-9
- Formula:C94H159N19O34
- Molecular Weight:2099.37
SMILES: C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N1[C@H](C(N[C@H](C(N)=O)C)=O)CCC1)CO)=O)C)=O)CCC(O)=O)=O)CCC(O)=O)=O)CCC(N)=O)=O)C)=O)CO)(=O)[C@H]2N(C([C@@H](NC(CNC([C@@](NC([C@@H](NC(CCOCCOCCNC(CCOCCOCCNC(CC[C@H](NC(CCCCCCCCCCCCCCCCCCC(O)=O)=O)C(O)=O)=O)=O)=O)[C@H](C)C)=O)(CC)C)=O)=O)CO)=O)CCC2
Biological Activity: LXJ-02 is a potent inhibitor of EDPs/EBP peptide–protein interaction, with the KD of 117 μM for EDPs. LXJ-02 activates the macrophage-MMP-12 axis to increase MMP-12 expression and degrade ECM components like elastin[1].
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LXJ-02 | LXJ-02 is a potent inhibitor of EDPs/EBP peptide–protein interaction, with the KD of 117 μM for EDPs. LXJ-02 activates the macrophage-MMP-12 axis to increase MMP-12 expression and degrade ECM components like elastin. | |||||||||||||||||||||
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Keywords
