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Cat. No.: HY-P6183

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LXJ-02

LXJ-02 is a potent inhibitor of EDPs/EBP peptide–protein interaction, with the K_D of 117 μM for EDPs. LXJ-02 activates the macrophage-MMP-12 axis to increase MMP-12 expression and degrade ECM components like elastin.

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CAS No.: 2672508-37-9
Formule: C₉₄H₁₅₉N₁₉O₃₄
Masse moléculaire:2099.37

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Please store the product under the recommended conditions in the Certificate of Analysis.

LXJ-02 Chemical Structure

CAS No.: 2672508-37-9

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Description

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Chemical Information

CAS No. 2672508-37-9
Masse moléculaire 2099.37
Formule C₉₄H₁₅₉N₁₉O₃₄
Sequence

{PEG2-PEG2}-{gamma-Glu}-{CO(CH2)18CO2H)}-Val-{Iva}-Gly-Ser-Pro-Ser-Ala-Gln-Glu-Glu-Ala-Ser-Pro-Ala-NH2
Sequence Shortening

{PEG2-PEG2}-{gamma-Glu}-{CO(CH2)18CO2H)}-V-{Iva}-GSPSAQEEASPA-NH2
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (259 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Yixiang Wang, et al. Design and Synthesis of Novel Ultralong-Acting Peptides as EDP-EBP Interaction Inhibitors for Pulmonary Fibrosis Treatment. J Med Chem. 2024 Apr 25;67(8):6624-6637. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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LXJ-02

Voir tous les produits spécifiques à Isoform MMP

Activité biologique

Description

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

LXJ-02 Related Classifications

HY-P6183 Related Classifications

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