2673196-75-1
Chemical Structure
JAK3/BTK-IN-5
- CAS No.: 2673196-75-1
- Formula:C19H22ClN7O2
- Molecular Weight:415.88
IUPAC Name: 1-((2S,4R)-4-((5-chloro-2-((1-ethyl-1H-pyrazol-4-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy)-2-methylpyrrolidin-1-yl)prop-2-en-1-one
InChIKey: VBHTYKLWZKIOEE-WCQYABFASA-N
SMILES: C=CC(N1[C@@H](C)C[C@@H](OC2=C3C(NC=C3Cl)=NC(NC4=CN(CC)N=C4)=N2)C1)=O
Biological Activity: JAK3/BTK-IN-5 is a potent inhibitor of JAK3/BTK. BTK and JAK3 are two important targets for autoimmune diseases. Simultaneous inhibition of the BTK/JAK3 signalling pathway exhibits synergistic effects. JAK3/BTK-IN-5 has the potential for the research of JAK3 kinase and/or BTK-related diseases (extracted from patent WO2021147953A1, example 35)[1]
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JAK3/BTK-IN-5 | JAK3/BTK-IN-5 is a potent inhibitor of JAK3/BTK. BTK and JAK3 are two important targets for autoimmune diseases. Simultaneous inhibition of the BTK/JAK3 signalling pathway exhibits synergistic effects. JAK3/BTK-IN-5 has the potential for the research of JAK3 kinase and/or BTK-related diseases (extracted from patent WO2021147953A1, example 35) | |||||||||||||||||||||
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Keywords
