2677762-43-3

HIV-1 inhibitor-45 Chemical Structure
2677762-43-3

Chemical Structure

HIV-1 inhibitor-45

  • CAS No.: 2677762-43-3
  • Formula:C23H24N4O8S
  • Molecular Weight:516.52

IUPAC Name: 4-((4-aminophenyl)sulfonyl)-N-(furan-2-ylmethyl)-1-(3,4,5-trihydroxybenzoyl)piperazine-2-carboxamide

InChIKey: RBSXWZYRKATMTP-UHFFFAOYSA-N

SMILES: O=C(C1N(C(C2=CC(O)=C(O)C(O)=C2)=O)CCN(S(=O)(C3=CC=C(N)C=C3)=O)C1)NCC4=CC=CO4

Biological Activity: HIV-1 inhibitor-45 is a potent HIV-1 RNase H inhibitor with an IC50 value of 0.067 μM. HIV-1 inhibitor-45 shows an antiviral activity. HIV-1 inhibitor-45 shows poor cell permeability (with an apparent permeability coefficient (Papp) lower than 0.48 × 10−6 cm/s)[1].

Cat. No. Product Name Purity Description Pricing
HY-150759
HIV-1 inhibitor-45 99.54% HIV-1 inhibitor-45 is a potent HIV-1 RNase H inhibitor with an IC50 value of 0.067 μM. HIV-1 inhibitor-45 shows an antiviral activity. HIV-1 inhibitor-45 shows poor cell permeability (with an apparent permeability coefficient (Papp) lower than 0.48 × 10−6 cm/s).
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