2681278-07-7
2681278-07-7
Chemical Structure
IRAK4-IN-9
- CAS No.: 2681278-07-7
- Formula:C22H25N7
- Molecular Weight:387.48
IUPAC Name: 3-(1-isopentyl-1H-1,2,3-triazol-4-yl)-4-(isopropylamino)-5H-pyrido[3,2-b]indole-7-carbonitrile
InChIKey: AUVOSQBQFDUNCH-UHFFFAOYSA-N
SMILES: N#CC1=CC2=C(C=C1)C3=NC=C(C4=CN(CCC(C)C)N=N4)C(NC(C)C)=C3N2
Biological Activity: IRAK4-IN-9 (compound 73) is a potent IRAK4 inhibitor with an IC50 of 1.5 nM. IRAK4-IN-9 blocks MyD88 dependent signaling. IRAK4-IN-9 has the potential for the research of inflammatory diseases, autoimmune diseases, and cancer[1].
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IRAK4-IN-9 | IRAK4-IN-9 (compound 73) is a potent IRAK4 inhibitor with an IC50 of 1.5 nM. IRAK4-IN-9 blocks MyD88 dependent signaling. IRAK4-IN-9 has the potential for the research of inflammatory diseases, autoimmune diseases, and cancer. | |||||||||||||||||||||
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References
Keywords
