268214-51-3
Chemical Structure
Coronalolide
- CAS. Nr.: 268214-51-3
- Formula:C30H42O5
- Molecular Weight:482.65
IUPAC Name: 3-((1aS,3aR,4R,6aS,6bS,7aR,10aR,10bR)-3a,6a-dimethyl-4-((R,E)-6-methyl-7-oxohept-5-en-2-yl)-10-methylene-9-oxododecahydro-1H-cyclopenta[7,8]cyclopropa[4,4a]naphtho[2,3-b]furan-10b(2H)-yl)propanoic acid
InChIKey: YLQIANWVVVMWMO-VDPDGNGOSA-N
SMILES: OC(CC[C@@]12[C@]3([C@](C[C@](O4)([H])[C@@]2([H])C(C4=O)=C)([H])[C@]5([C@@](C)([C@]([C@H](C)CC/C=C(C)/C=O)([H])CC5)CC3)C)C1)=O
Biological Activity: Coronalolide is a natural triterpene with anticancer effects. Coronalolide exhibits a broad cytotoxic activity for human breast (BT474), gastric (KATO-3), lung (CHAGO), colon (SW-620), and liver (Hep-G2) cancer cell lines, with IC50 values of 6.59 µg/mL, 5.85 µg/mL, 5.42 µg/mL, 4.98 µg/mL, and 6.41 µg/mL, respectively[1].
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Coronalolide | Coronalolide is a natural triterpene with anticancer effects. Coronalolide exhibits a broad cytotoxic activity for human breast (BT474), gastric (KATO-3), lung (CHAGO), colon (SW-620), and liver (Hep-G2) cancer cell lines, with IC50 values of 6.59 µg/mL, 5.85 µg/mL, 5.42 µg/mL, 4.98 µg/mL, and 6.41 µg/mL, respectively. | |||||||||||||||||||||
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Keywords
