2688882-69-9

PROTAC SMARCA2/4 degrader-37 Chemical Structure
2688882-69-9

Chemical Structure

PROTAC SMARCA2/4 degrader-37

  • CAS No.: 2688882-69-9
  • Formula:C37H31ClN8O6
  • Molecular Weight:719.15

InChIKey: IIYWQMYQROKRFZ-UHFFFAOYSA-N

SMILES: O=C(NC1=CC(C#CC2=CC=CC(C(NCCCCNC3=CC=CC(C(N4C5C(NC(CC5)=O)=O)=O)=C3C4=O)=O)=C2)=NC=C1)NC6=CC(Cl)=NC=C6

Biological Activity: PROTAC SMARCA2/4 degrader-37 (Example 4) is a PROTAC-based SMARCA2/4 degrader, with an IC50 of ≤0.1 μM (Pink: SMARCA2/4 lignad (HY-172446); Black: CRBN ligand (HY-41547); Linker (HY-N2407))[1].

Cat. No. Product Name Purity Description Pricing
HY-169861 		PROTAC SMARCA2/4 degrader-37 PROTAC SMARCA2/4 degrader-37 (Example 4) is a PROTAC-based SMARCA2/4 degrader, with an IC50 of ≤0.1 μM (Pink: SMARCA2/4 lignad (HY-172446); Black: CRBN ligand (HY-41547); Linker (HY-N2407)).
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