PROTAC SMARCA2/4 degrader-37
PROTAC SMARCA2/4 degrader-37 (Example 4) is a PROTAC-based SMARCA2/4 degrader, with an IC50 of ≤0.1 μM (Pink: SMARCA2/4 lignad (HY-172446); Black: CRBN ligand (HY-41547); Linker (HY-N2407)).
(Pink: SMARCA2 and SMARCA4 ligand (HY-172446); Blue: Cereblon ligand (HY-41547); Black: linker).
For research use only. We do not sell to patients.
- CAS No.: 2688882-69-9
- Formula: C37H31ClN8O6
- Molecular Weight:719.15
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cereblon |
Chemical Information
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CAS No. 2688882-69-9
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Molecular Weight 719.15
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Formula C37H31ClN8O6
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SMILES
O=C(NC1=CC(C#CC2=CC=CC(C(NCCCCNC3=CC=CC(C(N4C5C(NC(CC5)=O)=O)=O)=C3C4=O)=O)=C2)=NC=C1)NC6=CC(Cl)=NC=C6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)