2695505-82-7
2695505-82-7
Chemical Structure
RAF-IN-1
- CAS No.: 2695505-82-7
- Formula:C26H22F3N3O4
- Molecular Weight:497.47
InChIKey: PSMRBBKXSFUJFX-UHFFFAOYSA-N
SMILES: O=C(C1=CC(C(F)(F)F)=NC=C1)NC2=CC=C(C)C(C3=CC4=C(C(NC5(CCOCC5)O4)=O)C=C3)=C2
Biological Activity: RAF-IN-1 is a RAF inhibitor with IC50 values of 29.4 nM, 3.8 nM, and 36 nM against human recombinant bRAFV600E, cRAF, and bRAFWT enzymes, respectively. RAF-IN-1 suppresses RAF enzymatic activity and reduces cancer cell proliferation. RAF-IN-1 can be used for cancer research[1].
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RAF-IN-1 | RAF-IN-1 is a RAF inhibitor with IC50 values of 29.4 nM, 3.8 nM, and 36 nM against human recombinant bRAFV600E, cRAF, and bRAFWT enzymes, respectively. RAF-IN-1 suppresses RAF enzymatic activity and reduces cancer cell proliferation. RAF-IN-1 can be used for cancer research. | |||||||||||||||||||||
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References
Keywords
