2699607-49-1
2699607-49-1
Chemical Structure
CML-d3
Synonym(s): N6-(Carboxymethyl)-L-lysine-d3; Nε-(1-Carboxymethyl)-L-lysine-d3
- CAS No.: 2699607-49-1
- Formula:C8H13D3N2O4
- Molecular Weight:207.24
IUPAC Name: N6-(carboxymethyl)-L-lysine-2,6,6-d3
InChIKey: NUXSIDPKKIEIMI-SASOZDAZSA-N
SMILES: OC([C@](N)([2H])CCCC([2H])([2H])NCC(O)=O)=O
Biological Activity: CML-d3 is the deuterium labeled CML.
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CML-d3 | 99.0% | CML-d3 is the deuterium labeled CML. | ||||||||||||||||||||
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CML-d4 | 99.76% | CML-d4 is the deuterium labeled Fmoc-L-Lys (Boc)-OH. | ||||||||||||||||||||
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Nε-(Carboxymethyl)-L-lysine | 95.0% | Nε-(Carboxymethyl)-L-lysine (CML) is an orally active advanced glycation end product. Nε-(Carboxymethyl)-L-lysine upregulates the expression of PLK1 and CEP20, and induces the activation of RAGE and ERK/NFκB. Nε-(Carboxymethyl)-L-lysine drives centrosome amplification. Nε-(Carboxymethyl)-L-lysine induces malignant transformation of hepatocytes and promotes the development of hepatocellular carcinoma. Nε-(Carboxymethyl)-L-lysine induces epithelial-mesenchymal transition in osteosarcoma cells and enhances their migration and invasion properties. | ||||||||||||||||||||
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